With the difficulties associated with access to primary care and more aggressive emphasis on rapid hospital discharge and outpatient surgeries, sepsis ranks as one of the highest prevalence, highest mortality, and most expensive conditions that an emergency physician will encounter. Inthis publication, Dr. Andra Blomkalns provides up-to-date evidence on biomarkers for serious bacterial infection. Someof these biomarkers will be familiar to you while others may provide new insights into the diagnosis and treatment of this population. For the full CME webcast please visit our publications section at http://www.emcreg.org/education/cme/cme.html